Best Bet 12/22/2025
- Mason Dalley
- Dec 22, 2025
- 1 min read
San Francisco 49ers(-5.5) @ Indianapolis Colts
DK -110
FD -108
NFL Best Bet Season Record: 106-127-0
As fun as the Phillip Rivers thing is, I don't think he has the arm to keep up with a 49ers offense that is humming. The 49ers have been playing incredibly solid football and there's no reason to think that Grandpa Rivers can keep the Colts in the game. They'll need a Jonathan Taylor miracle game and there's no guarantee of that. 49er best bet.
If you or a loved one is experiencing problems with gambling, call (800) 327-5050 or visit https://gamblinghelplinema.org/ to speak with a trained specialist free and confidentially.
Comments